Dynamically Acquired 1H MRS for Detection of 13C Labeled Cerebral Glucose Metabolism In-vivo

Masoumeh Dehghani Presenter
McGill university
Montreal, Quebec 
Oral Sessions 
NMR spectroscopy has been used to probe metabolic pathways in vivo following infusion of specific 13Cā€enriched substrates. In the current study, we investigate the ability of the short TE SPECIAL sequence and the MEGA-PRESS J-editing sequence, without a 13C radiofrequency channel, to detect 13C labeled glucose metabolism in the brain, and we demonstrate for the first time its application in human participants.